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Polynucleotides

Polynucleotides are injectable treatments that support skin structure, firmness, and texture. They are particularly effective in delicate areas, such as the under-eye region, helping to improve the appearance of fine lines and promoting healthier, more resilient skin.

Procedure

45 Minutes

Price

From £275

Recovery

24 hours

Results

Gradual

Longevity

6–12 months

The treatment

All polynucleotide treatments at STORY Clinics are performed by Level 7 qualified aesthetic doctors, ensuring safe and precise results. Polynucleotides are derived from salmon DNA and work by stimulating fibroblasts, the cells responsible for collagen and elastin production. This process helps regenerate the skin’s structure, improve elasticity, and enhance overall skin quality.

Polynucleotides can be used as a standalone treatment or alongside other aesthetic procedures, such as dermal fillers, to support and prolong skin rejuvenation.

The procedure involves a series of micro-injections in targeted areas. You may notice small bumps or mild redness, which usually settle within 24 hours. Minor bruising can occasionally occur and typically fades within a few days.

Why a Course of Polynucleotides is Recommended

For optimal results, a course of three treatments spaced 2–4 weeks apart is recommended. The first session stimulates collagen and elastin production and improves skin quality, while subsequent sessions reinforce these effects for firmer, healthier-looking skin.

Real Results, Real Stories

Don’t just take our word for it, discover the experiences and results our patients have had at STORY Clinics. Want to share your own experience? Click here to leave a review for our Southwell Clinic or Marylebone Clinic.

Anne-Marie Chanthana

I’ve been coming to Story clinic for 4 years now. Everything is perfect, from the kindness of the receptionist to the professionalism of the doctors. Always very happy with my treatments. Visiting the clinic once a year is part of my annual routine.

Theo Lambrou

I’ve been coming to Story for a few years now and have always been happy with the results. Dr Tristan is very knowledgeable and consistently delivers natural results. Maja is lovely & professional. The reception team is also welcoming and polite every time.

Paula Gullett

Lovely clinic with great results from Dr Marcus. He takes the time to listen to you and always ensures natural results. I wouldn’t trust anyone else! She gives amazing advice, and I am always so extremely happy with my results.

Anne C

I’ve been coming to Story clinic for 4 years now. Everything is perfect, from the kindness of the receptionist to the professionalism of the doctors. Always very happy with my treatments. Visiting the clinic once a year is part of my routine.

Amir Sadegh

I’ve had several procedures done at Story Clinic and I can’t recommend them highly enough. What truly sets them apart is their integrity. Their advice is always honest, and it’s clear that their priority is your well-being, not profit.

Ellie H

I just had my first session of polynucleotides with Dr Sophie and the entire process was so lovely from start to finish. I had a thorough consultation, treatment was painless, and I finished feeling comfortable, relaxed, and ready to book my next session!

Cara Holtam

I couldn’t recommend Story more highly. They are a friendly, professional and incredibly knowledgeable skin care clinic, who offer a wide range of treatments. They make you feel very comfortable and relaxed and give results that show. Love it!

Paula Dececco

I've been coming to Story clinic in Southwell for years. Dr Heer is very professional, friendly and the clinic is doctor-led - it's very reassuring that they are level 7 trained, qualified, and knowledgeable. I am very pleased with my treatment.

Paula Dececco

I’ve recently had lip and cheek filler by Dr Harpreet in the Southwell Clinic. First of all the clinic is beautiful, it feels very homely, and the decor is stunning. I would absolutely recommend Dr Harpreet and Story Clinics and will definitely head back when I need my top-up.

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